| 蝮蛇抗栓酶对烧伤早期组织细胞损伤的影响 |
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| 引用本文： | 贺全勇.蝮蛇抗栓酶对烧伤早期组织细胞损伤的影响[J].中国烧伤创疡杂志,1999,0(2):8-11. |
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| 作者姓名： | 贺全勇 |
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| 作者单位： | 湖南医科大学附属三院!410013(贺全勇，罗成群)，湖南医科大学湘雅医院!410008(马恩庆) |
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| 摘 要： | 本研究针对烧伤后血液呈高凝状态，加重组织损害的特点，利用家兔25％TBSAⅢ°烫伤模型，采用蝮蛇抗栓酶治疗，观察脂质过氧化产物丙二醛（MDA）及血清酶学变化，结果显示：蝮蛇抗栓酶能明显减轻烧伤早期脂质过氧化损害；对烧伤后继发性组织损伤有保护作用。
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| 关 键 词： | 蝮蛇抗栓酶 烫伤 组织细胞损伤 |
The Effect of Ahylysantinfarctase (Svate) on Tissue Cell Injury at the Early Stage of Burn |
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| P<.: P<.; P<..The Effect of Ahylysantinfarctase (Svate) on Tissue Cell Injury at the Early Stage of Burn[J].The Chinese Journal of Burns Wounds & Surface Ulcers,1999,0(2):8-11. |
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| Authors: | P<: P<; P< |
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| Institution: | The 3rd Affiliated Hospital of Hunan Maedical University 410013 |
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| Abstract: | Rabbits with 25 % TBSA full-thickness burn produced by immersing the exposed area of the animal's back into 97oC boiling water for 13 seconds, were treated with Svate. The levels of malondialdehyde (MDA), lactic dehydrogenase (LDH), creatin kinase CK) and glutamic-oxalacetic transaminase (GOT) were measured at 5 minutes before scald and 2, 6, 12, 24, 48 hours after scald. This study suggested that Svate had significant protective effect on secondary tissue cell injury post burn. |
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| Keywords: | Svate MDA GOT CK LDH scald |
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