Nucleation of calcium phosphate by surface-bound extracellular matrix |
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| Authors: | Pham Minh Tan Maitz Manfred Franz Reuther Helfried Muecklich Arndt Prokert Friedrich Steiner Gerald |
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| Affiliation: | Forschungszentrum Rossendorf e.V., Institut für Ionenstrahlphysik und Materialforschung, Postfach 510119, 01314 Dresden, Deutschland. pham@fz-rossendorf.de |
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| Abstract: | The native extracellular matrix (ECM) laid down on silicon and titanium surfaces by osteoblast-like SAOS-2 cells was exposed by selective removal of cells. This type of material surface ECM-Si, ECM-Ti was shown to promote the nucleation of calcium phosphate from a simulated body fluid (SBF). Microscopic and spectroscopic results revealed the effect was associated with a collagen fiber-free extracellular matrix. |
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