Clinicopathological study of odontogenic keratocyst

Fifty-five cases of odontogenic keratocyst in the mandible were classified into two subtypes according to the histopathologic characteristics of the epithelium (Group-1; the epithelium was parakeratotic with cuboidal or columnar, accentuated and palisadelike arranged basal cells, Group-2; the epithelium was orthokeratotic with a distinct stratum granulosum.) and were examined for the following four factors; 1) age distribution, 2) size of bone destruction, 3) degree of lateral bone expansion, and 4) features of the cyst contents. Most cases of Group-1 indicated radiographically lateral bone expansion and large cystic bone destruction and had fluid cyst content. On the contrary, the majority of Group-2 cases indicated no lateral bone expansion, were relatively small lesions, and their cystic cavities were filled with caseous materials.