金花茶化学成分及药理作用研究进展

金花茶是山茶科山茶属中唯一具有金黄色花瓣的珍稀物种,其花和叶是我国民间传统用药,常用于咽喉炎,肾炎,黄疸型肝炎,痢疾,腹泻,高血压,尿路感染和月经不调等疾病的治疗,研究发现金花茶主要含有黄酮类成分,其中以槲皮素,山奈酚和它们的一些糖苷类衍生物为主,除黄酮类成分外,金花茶还含有多糖,植物多酚,皂苷类及挥发性物质等化学成分。体内及体外药理研究证明金花茶具有抗肿瘤,抗氧化,降血脂,降血糖,抗过敏,抗皮肤光老化以及抑菌等多种药理作用,本文全面综述了近年来金花茶植物化学成分和药理作用的研究进展,为金花茶资源的充分开发利用提供参考。

Chemical Constituents and Pharmacological Effects of Camellia nitidissima

Camellia nitidissima has attracted considerable attention as a rare and famous ornamental species characterized by yellow waxy petals in the genus Camellia of Theaceae. The flowers and leaves of C. nitidissima, a traditional herb in Chinese medicine, are commonly used for the treatment of faucitis, nephritis, hepatitis with jaundice, dysentery, diarrhea, hypertension, urinary tract infection and irregular menstruation. Studies have demonstrated that C. nitidissima mainly has flavonoid constituents, including quercetin,kaempferol and their glycoside Derivatives. In addition, C. nitidissima also has polyphenols, polysaccharides, saponins and volatile components. Both in vivo and in vitro pharmacological studies showed that C. nitidissima has anti-tumor, anti-oxidant, hypolipidemic, hypoglycemic, anti-allergy, anti-skin aging,anti-bacterial, and other pharmacological effects. The present paper presents the research progress of chemical composition and pharmacological effects of C. nitidissima in recent years, and provide theoretical evidence for the full development and utilization of C. nitidissima resources.