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重症肌无力与麻醉
引用本文:王永光,张利东,徐建国. 重症肌无力与麻醉[J]. 医学研究生学报, 2003, 16(6): 472-474
作者姓名:王永光  张利东  徐建国
作者单位:南京军区南京总医院麻醉科,江苏南京,210002
摘    要:
重症肌无力是抗体介导的自身免疫性疾病 ,以神经肌接头处 (又称运动终板 )突触后膜损害和功能性胆碱能受体减少所致的神经肌肉传导功能障碍为主要表现。胸腺切除术是治疗成人重症肌无力的有效方法之一。作者就重症肌无力病理生理特点及其与麻醉相关的诸多问题 ,如麻醉前病情的评估、术前治疗药物对麻醉的影响、重症肌无力患者对不同肌肉松弛药的反应与选用 ,以及麻醉恢复期的处理要点等予以综述

关 键 词:重症肌无力  麻醉
文章编号:1008-8199(2003)06-0472-03
修稿时间:2002-07-08

Myasthenia gravis and anesthesia
WANG Yong guang,ZHANG Li dong reviewing,XU Jian guo checking. Myasthenia gravis and anesthesia[J]. Bulletin of Medical Postgraduate, 2003, 16(6): 472-474
Authors:WANG Yong guang  ZHANG Li dong reviewing  XU Jian guo checking
Abstract:
Myasthenia gravis is an autoimmune disease resulting from the production of antibodies against acetylcholine receptors of the endplate. These antibodies impair postjunctional membrane and reduce the number of functional acetylcholine receptors of endplate. Thymectomy is an effective therapeutic method for adult myasthenic patients. In this paper, the author reviewed the pathophysiological characteristics and problems related to anesthesia, such as preoperative evaluation, the effect of preoperative medical treatment on the anesthesia, patients'response to muscle relaxants and postoperative management.
Keywords:Myasthenia gravis  Anesthesia
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