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| 生长抑素在乳腺癌中的表达及其临床意义 | |
| 引用本文： | 邓念英,伍尚标,方云光,刘少颜. 生长抑素在乳腺癌中的表达及其临床意义[J]. 中华实验外科杂志, 2001, 18(1): 29-30 |
| 作者姓名： | 邓念英 伍尚标 方云光 刘少颜 |
| 作者单位： | 广州市第二人民医院普外科 |
| 摘 要： | 目的 探讨生长抑素（ｓｓｔ）在乳腺癌中诊断和治疗的价值。方法 应用免疫组织化学方法对３０例原发性乳腺癌患者行ｓｓｔ和ＥＲＰＲ的表达。结果 有同侧腋窝淋巴结转移患者１１例，其中８例ｓｓｔ（＋）；无同侧腋窝淋巴结转移者１９例，其中７例ｓｓｔ（＋），两组差异有显著性（χ＾２＝３．６，Ｐ〈０．０５）。良性乳腺瘤１０例；其中４例ｓｓｔ（＋）与２０例乳腺癌ｓｓｔ（＋）相比，两组差异有非常显著性（χ＾２＝９．２２，Ｐ〈０．０１）。结论 ｓｓｔ对原发性乳腺癌诊断及治疗有一定的潜力。 |
| 关 键 词： | 乳腺肿瘤 生长抑素 免疫组织化学 基因表达 诊断 治疗 |
| 修稿时间： | 2000-05-21 |
Expression of somatostatin(SST) in breast cancer |
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| DENG Nianying,WU Shangbiao,FANG Yunguang,et al.. Expression of somatostatin(SST) in breast cancer[J]. Chinese Journal of Experimental Surgery, 2001, 18(1): 29-30 | |
| Authors: | DENG Nianying WU Shangbiao FANG Yunguang et al. |
| Affiliation: | DENG Nianying,WU Shangbiao,FANG Yunguang,et al. Department of Surgery,Second Peoples Hospital Guangzhou,Guangzhou 510150,China [ |
| Abstract: | Objective To evaluate the expression of Somatostatin(SST) in diagnoses and Treatment of breast cancer.Method 30 cases of primary breast cancer were studied in expression of Somatostatin(SST) and ER, PR with Immunohistochemicaty assay.Result 20 cases of patients in total 30 cases demonstrate SST positive. 8 SST positive in 19 patients with lateral lymph node negative. (χ2=3.6 P＜0.05). Compared with 10 cases of benign lesion of breast in which 4 cases show SST positive, 20 cases show SST positive in 30 cases of malignant lesions(χ2=9.22 P＜0.01).Conclusion Somatostatin(SST) plays a role diagnosis and treatment of primary breast cancer, but had better prognosis in patients with SST breast cancer. |
| Keywords: | Breast neoplasms Somatotatin Immunohistochemistry4 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |