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| 烧伤中分子物质对豚鼠心肌线粒体膜流动性影响的实验研究 | |
| 引用本文： | 董为人 叶本兰. 烧伤中分子物质对豚鼠心肌线粒体膜流动性影响的实验研究[J]. 中国病理生理杂志, 1993, 9(3): 404-407 |
| 作者姓名： | 董为人 叶本兰 |
| 作者单位： | 第一军医大学，第一军医大学，第一军医大学，第一军医大学，第三军医大学，第三军医大学 广州 510515，广州 510515，广州 510515，广州 510515 |
| 摘 要： | 本文应用从正常和烧伤豚鼠血中提取的中分子物质(NMMS,BMMS),以不同浓度干扰豚鼠心肌线粒体,观察中分子物质对线粒体膜流动性的影响。结果表明,NMMS和BMMS,尤其是BMMS在一定浓度下显著抑制膜流动性。作者认为,BMMS参与了烧伤后心泵功能障碍的病理机制。 |
| 关 键 词： | 毒素 心肌 线粒体 荧光分析 烧伤 |
Experimental study on effect of plasma middle molecules produced by burn on membrane fluidity of myocardic mitochondria in guinea pigs |
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| Dong Wei-Ren,Wang Tie-Dan,et al First Mil Med Univ,Guangzhou. Experimental study on effect of plasma middle molecules produced by burn on membrane fluidity of myocardic mitochondria in guinea pigs[J]. Chinese Journal of Pathophysiology, 1993, 9(3): 404-407 | |
| Authors: | Dong Wei-Ren Wang Tie-Dan et al First Mil Med Univ Guangzhou |
| Abstract: | The effect of plasma middle-molecule substances produced by burn (BMMS)at various concentrations on membrane fluidity of myocardic mitochondria of guinea pigswas studied and was compared with that of normal middle-molecule substances (NMMS).The result showed that, the membrane fludity of myocardic mitochondria was significant-ly decreased when it was incubated with either NMMS or BMMS at certain levels, espe-cially signficant with the latter. It was suggested that BMMS may play an importantrole in cardiodepression in thermal trauma. |
| Keywords: | Burns Toxins Myocardium Mitochondria Membrane fluidity Fluorometry |
| 本文献已被 CNKI 维普 等数据库收录！ | |