卡托普利联合美托洛尔治疗慢性心力衰竭临床疗效观察

目的评价在常规强心、利尿治疗基础上,卡托普利与美托洛尔治疗慢性充血性心力衰竭的疗效。方法选择慢性充血性心力衰竭病人90例,随机分为观察组与对照组,观察组（45例）在常规治疗的基础上,加用卡托普利与美托洛尔,观察8周。对照组（45例）为常规治疗组,常规给予地予高辛和利尿剂治疗。结果3年间,治疗组与对照组有效率分别为86.67%和66.67%,差异具有统计学意义（P〈0.05）,治疗组与对照组左室收缩末期内径、左室舒张末期内径、左室射血分数均有显著差别,P〈0.01,治疗组比对照组疗效显著。结论卡托普利联合美托洛尔治疗慢性充血性心力衰竭临床疗效更好。

The clinical observation of the treatment for chronic heart failure by Captopril combined with Metoprolol

Objective To evaluate the conventional cardiac,diuretic therapy,captopril and metoprolol in the treatment of chronic congestive heart failure.Methods 90 cases of patients with chronic congestive heart failure were randomly divided into two groups:the control group and the observation group(with 45 cases each).on the basis of conventional treatment,it had the addition of captopril and metoprolol.it was observed for 8 weeks.The control group(45 oases)has the conventional treatment with digoxin and diuretic.Results With 3 years,the treatment group and control group effective rate was 86.67% percent and 66.67% percent respectively.Treatment group and control group left ventricular end systolic diameter,left ventricular end diastolic diameter,left ventricular ejection fraction have significant difference,P<0.01,there were significant effect in the treatment group compared with the control group.Conclusions The treatment of captopril combined with metoprolol for the chronic congestive heart failure can improve the clinical efficacy.