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Detection of Prosthetic Joint Infection by Use of PCR-Electrospray Ionization Mass Spectrometry Applied to Synovial Fluid |
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| Authors: | Dante P. Melendez James R. Uhl Kerryl E. Greenwood-Quaintance Arlen D. Hanssen Rangarajan Sampath Robin Patel |
| Affiliation: | aDivision of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA;bDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA;cDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA;dIbis Biosciences, Abbott Company, Carlsbad, California, USA |
| Abstract: | PCR coupled with electrospray ionization mass spectrometry applied to synovial fluid specimens had an 81% sensitivity and a 95% specificity for the diagnosis of prosthetic joint infection. |
| Keywords: | |