Wolf's Isotopic Response: Report of a Case and Review of Literature |
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| Authors: | Rahul Mahajan Dipankar De Uma Nahar Saikia |
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| Affiliation: | From the Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India;1.Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India |
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| Abstract: | “Wolf''s isotopic response” refers to the occurrence of a new dermatosis at the site of previously healed dermatosis. A number of factors including viral, neural, vascular, and immunologic factors have been implicated in the causation of this peculiar response but none has been proven conclusively. Here, we report a case where lichen planus developed at the site of dermatofibrosarcoma protruberans that had been previously treated with surgery and radiotherapy. We also put forth a hypothesis on the genesis of isotopic response considering the above mentioned factors. |
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| Keywords: | Immune response isotopic response dermatofibrosarcoma protuberans lichen planus |
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