Practical points in the application of oxygen transport principles

Application of the principles of oxygen transport in the management of critically ill patients can influence the frequency of organ failure and outcome. Adequate tissue oxygen consumption in these patients may depend on a supranormal level of oxygen delivery. The equations used for calculating oxygen delivery and consumption are provided, and it is noted that clinicians should have a clear understanding of the limitations of each of the measurements included in the equations. The methods used to perform the measurements are reviewed. Widespread acceptance and use of oxygen transport protocols in treatment is only possible if the measurements on which they are based are accurate and properly interpreted.