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| 采用抽吸取精法结合单精子注射治疗无精子症结局 | |
| 引用本文： | 刘雅峰,欧建平,钟依平,徐艳文,苗本郁,李洁,周灿权. 采用抽吸取精法结合单精子注射治疗无精子症结局[J]. 中国优生与遗传杂志, 2012, 0(6): 98-99 |
| 作者姓名： | 刘雅峰 欧建平 钟依平 徐艳文 苗本郁 李洁 周灿权 |
| 作者单位： | 中山大学附属第一医院生殖医学中心 |
| 基金项目： | 广东省科技计划项目,编号:2010B031600081 |
| 摘 要： | 目的评价经皮附睾精子抽吸术（percutaneus epididymal sperm aspiration,PESA）或睾丸精子抽吸术（testicular sperm aspiration,TESA）结合卵胞浆内单精子注射（intracytoplasmic sperm injection,ICSI）治疗无精子症的临床效果。方法对290例因男性梗阻性及非梗阻性无精子症（non-obstructive azoospermia,NOA）采用PESA或TESA穿刺获取精子,女方采用长方案超排卵,然后对处于细胞分裂中期的成熟卵母细胞进行单精子注射。结果梗阻性无精子症组203例,受精率77.5%,临床妊娠率46.1%;非梗阻性无精子症组87例,受精率73.0%,临床妊娠率41.4%,两组比较其受精率及临床妊娠率均无显著性差异（P〉0.05）。结论采用PESA或TESA获取精子结合ICSI是治疗梗阻性及非梗阻性无精子症等严重的男性不育症的一种有效的方法。 |
| 关 键 词： | 无精子症 附睾或睾丸抽吸取精 卵胞浆内单精子注射 |
Study of PESA/TESA with ICSI in azoospermia patients |
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| LIU Ya-feng,OU Jian-ping,ZHONG YI-ping,XU Yan-wen,MIAO Ben-yu,LI Jie,ZHOU Can-quan. Study of PESA/TESA with ICSI in azoospermia patients[J]. Chinese Journal of Birth Health & Heredity, 2012, 0(6): 98-99 | |
| Authors: | LIU Ya-feng OU Jian-ping ZHONG YI-ping XU Yan-wen MIAO Ben-yu LI Jie ZHOU Can-quan |
| Affiliation: | .(Center for Reproductive Medcine,The First Affiliated Hospital of Sun Yat-Sen Unversituy,Guangzhou 510080,China) |
| Abstract: | Objective: To investigate the effect of PESA/TESA with ICSI for azoospermia patients.Methods: 290 male cases with obstructive and non-obstructive azoospermia accepted PESA/TESA with ICSI,While their wives received conventional ovarian hyperstimulation.All oocytes contained MⅡ were injected.Results: The fertility rate(FR) and clinical prognency rate(PR) in obstructive azoospermia men were 77.5% and 46.1% respectively;In non-obstructive azoospermia group,the FR and PR were respectively 73.0% and 41.4%.The two groups had no statistic difference(P>0.05).Conclusions:PESA/TESA with ICSI has provided a rapid,convenient and effective treatment for obstructive and non-obstructive azoospermia men. |
| Keywords: | Male infertility PESA/TESA ICSI |
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