手工与机采血小板疗效的临床观察

目的 比较手工血小板和机采血小板的疗效,为临床输血提供参考依据.方法 样本来源于该院经过血小板输注治疗的住院患者,其中134例患者输用6 756 U手工血小板为A组;74例患者输用2 880 U机采血小板为B组.分别观察两组患者输注24 h后血小板校正增加指数（CCI）、血小板回收率（PPR）、临床出血症状有无改善、有无输血反应等进行输注后疗效判断.结果 与B组比较,A组CCI、PPR、总的输注有效率、输注反应率比较差异均无统计学意义（P〉0.05）.结论 对于未产生同种免疫的患者,输注手工血小板或机采血小板,具有同等的安全性和有效性.因此,手工血小板的应用能够节约血液资源,缓解血小板供应紧张的现状.

Clinical observation for therapeutic effect of manual platelets and apheresis platelets

Objective To observe therapeutic effect of manal platelets and apheresis platelets, clinical transfusion may be sup- ported. Methods Samples were from patients with platelet transfusion in hospital. 134 patients were infused 6 756 U manal plate- lets（group A）, 74 patients were infused 2 880 U apheresis platelets（group B）. After 24 hours of infusion, platelets corrected count increment （CCI）, percentage platelet recovery （PPR）, hemorrhage, and transfusion reaction were observed in group A and B. Re- sults Compard with group B, CCI,PPR,hemorrhage and transfusion reaction were not obviously different in group A（P〉0.05）. Conclusion For the patients without generate allogenetic immunifaction, manal platelets and apheresis platelets are safe and effi- cient. So to apply manal platelets could save blood resources and release the demand.