南京地区哮喘儿童体外过敏原检测分析

目的 调查南京地区支气管哮喘患儿的主要过敏原.方法 采用德国Mediwiss 过敏原体外检测系统,检测南京地区436例过敏支气管哮喘患儿血清总IgE 和各种特异性IgE的含量.结果 血清总IgE阳性率为83.5%,吸入性过敏原组阳性率为79.3%（螨虫66.7%、猫狗毛皮屑25.3%、霉菌组合15.1%、草粉组合为 7.3%）,食入性过敏原组阳性率为21.7%（鸡蛋为 14.1%、牛奶为10.2%）.结论 尘螨是南京地区儿童过敏性鼻炎最主要的过敏原,过敏原检测可指导患儿家长避免患儿接触或消除引起哮喘发作的诱发因素,同时为进一步开展特异性的免疫治疗提供科学依据.

Analysis of allergens in children with bronchial asthma in Nanjing by in vitro detection

Objective To investigate the main allergens in children with bronchial asthma in Nanjing. Methods German Medi- wiss allergen detection system in vitro was used to detect the contents of serum total IgE level and variant specific serum IgE levels in 436 cases of children with bronchial asthma. Results The positive rate of serum total IgE was 83.5%. The inhaled allergens pos- itive rate was 79.3% ,which could be list as follows：dust mite（66. 7%）,canine and feline scurf（25. 3%）, fungus（15.1%）, grass powder （7.3 % ）, the positive rate of food allergens was 21.7 %, which could be list as follows ： egg（14.1 %） and milk（10.2 % ）. Con- clusion Dust mite is one of the most important allergens in children with bronchial asthma in Nanjing. Allergen detection can be parents guide children to avoid contact or to eliminate the cause of inducing factors in children with asthma,at the same time to pro- vide the scientific basis for the further development of specific immunotherapy.