| 中青年急性脑梗死患者血浆同型半胱氨酸水平和超敏C反应蛋白与颈动脉粥样硬化的关系 |
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| 引用本文： | 周俊山,徐梦怡,陆敏. 中青年急性脑梗死患者血浆同型半胱氨酸水平和超敏C反应蛋白与颈动脉粥样硬化的关系[J]. 脑与神经疾病杂志, 2011, 19(2) |
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| 作者姓名： | 周俊山 徐梦怡 陆敏 |
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| 作者单位： | 南京医科大学附属南京市第一医院神经内科,南京,210006 |
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| 基金项目： | 南京市医学科技发展项目 |
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| 摘 要： | 目的探讨中青年急性脑梗死(ACI)患者血浆同型半胱氨酸(Hcy)水平和超敏C反应蛋白(hs-CRP)与颈动脉粥样硬化(CAS)斑块及其硬化程度的关系。方法对入选144例中青年ACI患者进行颈动脉超声,测量颈动脉内中膜厚度(IMT)并观察有无斑块之间的相关性分析。结果中青年急性脑梗死(ACI)合并颈动脉粥样硬化的患者血清Hcy、hs-CRP明显高于无颈动脉硬化患者(P<0.05)。有CAS斑块的患者血清Hcy、hs-CRP显著高于颈动脉内中膜正常与增厚患者(均为P<0.05)。CAS程度:0级组、1级组分别与3级组,0级组、1级组、2级组分别与4级组的血清Hcy、hs-CRP水平比较差异有统计学意义(均P<0.05)。结论血清Hcy、hs-CRP水平与中青年急性脑梗死(ACI)患者颈动脉粥样硬化的发生有一定相关性,CAS程度愈重,其相关性愈大。
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| 关 键 词： | 中青年 脑梗死 超敏C反应蛋白 同型半胱氨酸 颈动脉粥样硬化 |
Analysis of relationship between plasms homocysteine,high-sensitivity C-reactive protein and carotid atherosclerosis in young adult cerebral infarction |
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| ZHOU Jun-shan,XU Meng-yi,LU Min. Analysis of relationship between plasms homocysteine,high-sensitivity C-reactive protein and carotid atherosclerosis in young adult cerebral infarction[J]. Journal of Brain and Nervous Diseases, 2011, 19(2) |
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| Authors: | ZHOU Jun-shan XU Meng-yi LU Min |
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| Affiliation: | .Department of Neurology; Nanjing First Hospital Affiliated to Nanjing Medical University; Nanjing 210006; China; |
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| Abstract: | Objective To investigae the correlation between the plasma homocysteine(Hcy)and high sensitivity C-reactive protenin(hs-CRP)level and the plaque and its deree of the carotid atherosclerosis(CAS) in young patients with acute cerebral infarction(ACI).Methods Totally 144young patients with acute cerebral infarction were examined by B-mode ultrasound to measture intima media thickness(IMT) of the common carotid artery and plaqur formation.The plasmsa Hcy and hs-CRP of these patients were tected.Then patients we... |
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| Keywords: | Young adult Cerebral infarction High-sensitivity C-reactive protein Homocysteine |
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