院内鲍曼不动杆菌感染患者预后危险因素分析

目的 探讨院内鲍曼不动杆菌(AB)感染患者的预后危险因素.方法 回顾性分析141例院内AB感染患者的病例资料,以随访患者确诊为AB感染后60 d临床结局为依据分为死亡组(53例)和存活组(88例),同时收集患者的相关临床病例资料,通过COX回归分析确定影响AB感染患者的预后独立危险因素.结果 单因素分析得出AB感染患者的预后危险因素包括:年龄、是否入住ICU、长期卧床、胃管、碳青霉烯类使用、糖肽类使用、合并革兰阳性(G+)菌感染、合并革兰阴性(G-)菌感染、器官功能不全、急性生理与慢性健康评分(APACHE-Ⅱ)差值和序贯性脏器衰竭评价评分(SOFA)差值;多因素分析得出碳青霉烯类使用、合并G-菌感染、器官功能不全和APACHE-Ⅱ评分差值是AB感染患者预后的独立危险因素.结论 院内AB感染患者预后的独立危险因素为碳青霉烯类使用、合并G-菌感染、器官功能不全和APACHE-Ⅱ评分差值.

Hospital's analysis on prognostic risk factors affecting acquired acinetobacter baumannii infected patients

Objective Study of analysis on prognostic risk factors affecting Acinetobacter baumannii(AB)infected patients.Methods By retrospective analysis on 141 cases of acquired AB infected patients in a general 3A hospital during from January of 2015 to Decem-ber of 2016,based on the clinical outcomes of 60 d after the follow-up patients diagnosed as the AB infected,they were separated to the deceased group(53 cases)and survived group(88 cases),and collected relevant clinical documents of them.Through COX regression analysis,to determine the prognostic risk independent factors affecting AB infected patients.Results The single-factor analysis showed that the prognostic risk factors of AB infected patients embrace:age,whether having stayed in ICU,long-term bed,stomach tube,taking Carbopenems,using glycopeptides,Gram positive,Gram negative,organ dysfunction,APACHE-Ⅱ score difference and SOFA score difference.The multi-factor analysis indicated that taking Carbopenems,Gram positive infection,organ dysfunction,APACHE-ⅡCscore difference were the prognostic independent risk factors influencing AB infected patients.Conclusions The independent risk factors, having impact on death of hospital acquired AB infected patients,embrace taking Carbopenems,Gram positive infection,organ dysfunc-tion and APACHE-Ⅱscore difference.