| MODS患儿血清磷酯酶A2的变化及意义 |
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| 引用本文： | 潘国权,陈小剑,严纯雪,黄建芬.MODS患儿血清磷酯酶A2的变化及意义[J].河北医学,2002,8(5):423-425. |
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| 作者姓名： | 潘国权 陈小剑 严纯雪 黄建芬 |
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| 作者单位： | 温州医学院附属育英儿童医院,浙江,温州,325027 |
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| 摘 要： | 目的：探讨磷酯酶A2（PLA2）在多脏器功能障碍综合征（MODS）患儿中的作用及意义。方法：结合危重病例评分，采用ELISA法检测26例MODS患儿血清PLA2含量，并与健康体检儿童20例对照。结果：多脏器功能障碍综合征患儿血清PLA2含量明显高于正常对照组，P＜0．01，并与危重病例评分成正相关。结论：PLA2参与MODS的病理生理过程，与危重病的病情有关，并可作为早期预警多脏器功能障碍综合征的实验参数。
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| 关 键 词： | MODS 血清 儿童 多脏器功能障碍综合征 磷酯酶A2 PLA2 |
| 文章编号： | 1006-6233(2002)05-0423-03 |
The role and significance of phospholipase A2 in children with multiple organ dysfunction syndrome |
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| PAN Guo-quan,CHEN Xiao,YAN Chue-xue,et al.The role and significance of phospholipase A2 in children with multiple organ dysfunction syndrome[J].Hebei Medicine,2002,8(5):423-425. |
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| Authors: | PAN Guo-quan CHEN Xiao YAN Chue-xue |
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| Abstract: | Objective:To investigate the action and significance of phospholipase A 2 (PlA 2) in the pejorative process of Children with multiple organ dysfunction syndrome(MODS). Methods: Combined with the critical care scores, Serum concentrations of PLA 2 were determined 26 children with MODS and 20 healthy children by ELISA method. Results: Serum concentrations of PLA 2 in MODS were significantly higher than these in healthy children (P>0.01), and the serum PLA 2 level correlated directly with the critical care scores. Conclusion: PLA 2 are involved in the Pathophysiologic process of MODS. PLA 2 are a laboratory parameter to alarm to the development of MODS. |
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| Keywords: | Child Multiple organ dysfunction syndrome Phospholipase A 2(PLA 2) |
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