Acute heart failure and acute renal failure in Kawasaki disease |
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| Authors: | HIDEAKI SENZAKI MATSUKO SUDA SEIJI NOMA HARUO KAWAGUCHI YOICHI SAKAKIHARA TOSHIO HISHI |
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| Institution: | 1. Department of Pediatrics, Toho Medical College, Tokyo, Japan;2. Hachioji Children's Hospital, Tokyo, Japan;3. Laboratory of System Physiology, Department of Pediatrics, University of Tokyo, Japan |
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| Abstract: | Acute renal failure and acute heart failure are rare in Kawasaki disease. We experienced two patients with Kawasaki disease who presented acute renal failure and acute heart failure. These two patients gave us an important insight into the understanding of water balance and fluid therapy in Kawasaki disease. One patient showed acute prerenal failure due to fluid exudation from the intravascular to the extravascular space, and subsequent acute heart failure. The other patient showed acute heart failure caused by fluid infusion for the treatment of dehydration. It is suggested that acute renal failure could be caused by a fluid shift from the intravascular to the extravascular space in Kawasaki disease. It is also demonstrated that the reserve of cardiac function could be decreased in patients with Kawasaki disease due to myocarditis even with normal echocardiography and chest X-rays. |
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| Keywords: | acute heart failure acute renal failure increased vascular permeability Kawasaki disease |
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