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北京市崇文区健康人群麻疹抗体水平调查
引用本文:鲍亚范,王幼兰,高鹏,胡玉清,赵秀芬,李学荣. 北京市崇文区健康人群麻疹抗体水平调查[J]. 中国疫苗和免疫, 1999, 0(4)
作者姓名:鲍亚范  王幼兰  高鹏  胡玉清  赵秀芬  李学荣
作者单位:北京市崇文区卫生防疫站!北京市,100050,北京市崇文区卫生防疫站!北京市,100050,北京市崇文区卫生防疫站!北京市,100050,北京市崇文区卫生防疫站!北京市,100050,北京市崇文区卫生防疫站!北京市,100050,北京市崇文区卫生防疫站!北京市,100050
摘    要:
为了解崇文区健康人群麻疹抗体水平,对0~49岁479人进行了麻疹抗体水平监测.结果显示,抗体阳性率为75.37%(361/479),阳性率较高的人群是1岁和20~29岁,分别是98.33%和93.33%;较低的是6月龄儿童,阳性率为1.69%.各年龄组间抗体阳性率的有极显著的统计学意义(P<0.001).从抗体水平看:以低抗体(1:200)为主,占44.68%,中抗体(1:800)占23.38%,高抗体(1:3200)占了30%;抗体几何平均滴度倒数(GRT)为246.72.抗体清度水平的的高低与阳性率分布一致,仍有24.64%的人处于易感水平,主要是6月龄儿童.这部分人群中有98.31%的人抗体水平<1:200.其中<1:50的占72.89%,1:50的占25.42%.经分析比较,其它年龄组抗体比较平衡稳定.因此今后预防的重点人群是6月龄儿童,建议麻疹疫苗(MV)初免提前至6月龄,并考虑可给婚前体检女青年进行MV免疫。

关 键 词:麻疹疫苗  免疫水平  监测

Analysis of Immune Levels of Measies in Different Age Groups of Population in Chongwen District of Beijing
BAO Ya-fan, WANG You-lan, GAO Peng,et al.. Analysis of Immune Levels of Measies in Different Age Groups of Population in Chongwen District of Beijing[J]. Chinese Journal of Vaccines and Immunization, 1999, 0(4)
Authors:BAO Ya-fan   WANG You-lan   GAO Peng  et al.
Abstract:
This study investigated the measles immune level of 479 healthy people from 0 -49yeals old. The total antibody positive rate was 75.37% (361/479). The groups with higher antibodypositive rates were 1 year old (98.33%) and 20 year old (93.33%) persons, and that with lowest positive rate was 6 month old children (1.69%), the difference among them was very distinctive(p<0.001). The survey also showed that 44.68% of the populahon inveStigated was at a lowerantiboldy level, 23.38% at moderate level and 7.31% at higher level, the average GMRT was246.72. The antibody level was in accordance with the measles antibody positive rate. 24.64% of thepersons were susceptible to measles, they were mainly children of 6 months old, of them 98.31% hadantibody level < 1:50(72.89%) and 1:50 (25.42%) were involved. This study indicated that the 6month old childal were sensitive to measles, so we suggest that it is betthe to begin the primary~non of measles in children of 6 months old.
Keywords:Measles vaccine   Immune level   Surveillance
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