结石通片的利尿和排石作用

目的：探讨结石通片的利尿和排石作用。方法：采用大鼠代谢笼法进行利尿实验。给予大鼠乙二醇和氯化铵。连续30d，以形成结石模型进行排石试验。结果：高、低剂量的结石通片组均有显著的利尿作用。3h内总尿量与对照组比较增加了约50%；给药组的大鼠结石形成率明显降低，且随着药物浓度的升高，排石作用更显著。结论：结石通片具有利尿和排石作用。

Diuresis and Removing Urinary Calculus Action of Jieshitong Tablet

Objective: Diuresis and removing urinary calculus action of Jieshitong tablet were studied. Methods: Metabolic cage method of rats was adopted to be engaged in diuresis experiment; glycol and ammonium chloride had been given orally for 30 days to form concretion model so that a removing urinary calculus trial could be done. Results: High and low doses of Jeshitong tablet both had significant diuresis effect, total urinary output in 3h of drug group increased about 50% than that of control group. Concretio formative rates of Jeshitong tablet group significantly decresed; the stronger removing urinary calculus action, the higher Jieshitong concentraction was. Conclusion: Jieshitong tablet had diuresis and removing urinary calculus action.