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Evaluation of the quality of life in patients followed for differentiated cancer of the thyroid
Authors:Nassim Essabah Haraj  Hicham Bouri  Siham El Aziz  Samira Nani  Noureddine Habti  Asma Chadli
Affiliation:1. Service d’endocrinologie et de maladies métaboliques, CHU Ibn Rochd, Casablanca, Morocco;2. Laboratoire de neuroscience clinique et santé mentale, faculté de médecine et de pharmacie de Casablanca, université Hassan II, Casablanca, Morocco;3. Laboratoire d’épidémiologie, faculté de médecine et de pharmacie de Casablanca, université Hassan II, Casablanca, Morocco;4. Laboratoire de médecine expérimentale et biotechnologie, Casablanca, Morocco;5. Laboratoire de génie génétique et cellulaire, faculté de médecine et de pharmacie de Casablanca, université Hassan II, Casablanca, Morocco
Abstract:Thyroid cancer often has good prognosis but can impact quality of life. The objective of this study is to evaluate quality of life in patients treated for differentiated thyroid carcinoma and look for associated factors. An observational cross-sectional study with comparison group was conducted in the Endocrinology Department of the Ibn Rochd University Hospital between October 2013 and February 2015. The patient group included 124 adult patients followed for differentiated thyroid carcinoma; the control group comprised 124 healthy subjects of the same age. Quality of life was evaluated by 3 questionnaires validated in Arabic: SF36, Hamilton anxiety and Hamilton depression. Patients’ quality of life was significantly impaired compared to controls on the two Hamilton and all SF36 scores. Factors influencing quality of life were TNM stage, radioiodine therapy and dose, and the presence of metastases. The psychological management of patients with thyroid cancer is an essential point always to be considered, especially in the presence of risk factors for impaired quality of life.
Keywords:Thyroid neoplasms  Quality of life  Radioiodine therapy  Cancer de la thyroïde  Qualité de vie  Irathérapie
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