| 生物钟基因与肿瘤时辰治疗的研究进展 |
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| 引用本文： | 熊娟,李光明. 生物钟基因与肿瘤时辰治疗的研究进展[J]. 陕西肿瘤医学, 2013, 0(11): 2622-2625 |
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| 作者姓名： | 熊娟 李光明 |
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| 作者单位： | [1]泸州医学院,四川泸州646000 [2]南充市中心医院,四川南充637000 |
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| 摘 要： | 近年来,生物钟基因及昼夜节律在肿瘤发生、发展及转移中的研究已成为肿瘤研究领域内的热点.生物钟基因普遍存在于生物界,是生物昼夜节律运转的分子基础.其表达紊乱会增加肿瘤的发病率,通过对肿瘤时间节律性及时间生物学的研究,对指导肿瘤的治疗、预后及转归开辟了一条新思路.本文就生物钟基因及肿瘤的时辰治疗研究进展作一综述.
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| 关 键 词： | 生物钟基因 肿瘤 时辰化疗 时辰放疗 |
Research advances of circadian clock genes and chronnotherapy |
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| Xiong JuanLuzhou Medical College,Sichuan Luzhou,China Li Guangming. Research advances of circadian clock genes and chronnotherapy[J]. Shaanxi Oncology Medicine, 2013, 0(11): 2622-2625 |
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| Authors: | Xiong JuanLuzhou Medical College Sichuan Luzhou China Li Guangming |
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| Affiliation: | Xiong Juan(Luzhou Medical College, Sichuan Luzhou 646000, China) Li Guangming(Nanchong Center Hospital, Sichuan Nanchong 637000, China) |
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| Abstract: | In recent times,much research has been directed toward studying the role of circadian clock genes and circadian rhythms in tumor development,growth and metastasis.Circadian clock genes,widespread in the biosphere,are the molecular basis of biological circadian rhythm.It can accelerate the growth and metastasis of tumor when the gene expression was disturbed.The research to the tumor circadian and chronobiology opened up a new idea for tumor treatment,prognosis and outcome.The aim of this review is to summarize the advance of circadian clock genes and chronnotherapy for tumor. |
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| Keywords: | circadian clock genes tumor chronomodulated chemotherapy chronomodulated radiotherapy |
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