| 大黄酸肠溶片的制备 |
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| 引用本文： | 童敏,谭梅英,朱永坤,詹利之.大黄酸肠溶片的制备[J].海峡药学,2016(6):7-9. |
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| 作者姓名： | 童敏 谭梅英 朱永坤 詹利之 |
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| 作者单位： | 1. 东莞市第三人民医院 东莞 523326;2. 广东省第二中医院 广州510095;3. 广州中医药大学青蒿研究中心广州510405 |
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| 摘 要： | 目的：研制大黄酸肠溶片。方法采用正交试验设计法，以包衣效率为指标，考察雾化压力、蠕动泵转速、枪床距离3个因素，优化大黄酸肠溶片的包衣工艺。结果最佳工艺参数，雾化压力4．5kg／cm2、蠕动泵转速1．5mL? min －1、枪床距离30cm。结论所制备的肠溶片符合设计要求，适合临床应用。
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| 关 键 词： | 大黄酸 肠溶片 制备工艺 |
Preparation of Rhein enteric Coated TabIets |
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| Abstract: | OBJECTIVE To study the preparation of rhein enteric coated tablets .METHODS Orthogonal ex-periment design was used to optimize the process of preparation , and atomization pressure , peristaltic pump speed , distance between spray gun and pan were investigated .RESULTS The optimal technical conditions were as fol-lows:atomization pressure 4.5kg/cm2 ,peristaltic pump speed 1.5mL? min -1 ,distance between spray gun and pan 30 cm.CONCLUSION The enteric coated tablets comply with the design requirement ,and suitable for clinical ap-plication. |
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| Keywords: | Rhein Enteric coated tablets Preparation technology |
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