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布地奈德治疗支气管哮喘急性发作的疗效观察
引用本文:刘晓华,孙米晔,向慧敏. 布地奈德治疗支气管哮喘急性发作的疗效观察[J]. 职业与健康, 2012, 28(20): 2551-2553
作者姓名:刘晓华  孙米晔  向慧敏
作者单位:中国人民武装警察部队内蒙古自治区总队医院内一科,呼和浩特市,010010
摘    要:目的观察对比氧气驱动雾化吸入布地奈德混悬液和静脉滴注琥珀酸氢化可的松治疗中、重度支气管哮喘急性发作的疗效。方法选取武警内蒙古总队医院收治的80例中、重度支气管哮喘急性发作患者,随机分为两组。在常规治疗的基础上一组雾化吸入布地奈德混悬液6 mg/d,另一组静脉滴注注射用琥珀酸氢化可的松200 mg/d。分别观察治疗前后和不同药物治疗哮喘的临床症状和肺功能指标的变化。结果两组患者临床症状和肺功能指标均明显改善,两组患者的疗效差异无统计学意义(P0.05);但治疗后对照组血糖水平较治疗组明显增高,差异有统计学意义(P0.05)。结论氧气驱动雾化吸入布地奈德和静脉滴注琥珀酸氢化可的松疗效基本相当,但使用布地奈德治疗支气管哮喘患者全身不良反应较小。

关 键 词:布地奈德混悬液  氧气驱动雾化吸入  支气管哮喘

Efficacy observation of budesonide on acute exacerbation of bronchial asthma
LIU Xiao-hua , SUN Mi-ye , XIANG Hui-min. Efficacy observation of budesonide on acute exacerbation of bronchial asthma[J]. Occupation and Health, 2012, 28(20): 2551-2553
Authors:LIU Xiao-hua    SUN Mi-ye    XIANG Hui-min
Affiliation:1 Department of Internal Medicine,General Hospital of Inner Mongolia Municipal Corps of Chinese People's Armed Police Force,Hohhot,010010,China
Abstract:[Objective]To compare the curative effect of oxygen-driven aerosol inhalation budesonide suspension and intravenous infusion of hydrocortisone sodium succinate on acute exacerbation of mild or severe bronchial asthma.[Methods]A total of 80 patients with acute exacerbation of mild or severe bronchial asthma in Armed Police Corps Hospital of Inner Mongolia were divided into 2 groups randomly.Based on routine treatment,one group was giving oxygen-driven aerosol inhalation budesonide suspension 6 mg/d,the other received intravenous infusion of hydrocortisone sodium succinate 200 mg/d.Changes in clinical symptoms and lung function indicators by different drugs were observed before and after treatments.[Results] Two groups of clinical symptoms and lung function indicators were markedly improved,the difference of the curative effect between 2 groups was not statistically significant(P0.05).But the blood glucose in treatment group was higher than the control group after treatment,the difference was statistically significant(P0.05).[Conclusion]There is no different curative effect between oxygen-driven aerosol inhalation budesonide suspension and intravenous infusion of hydrocortisone sodium succinate,but the systemic side effects in treatment group are smaller than the control group
Keywords:Budesonide suspension  Oxygen-driven aerosol inhalation  Bronchial asthma
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