素馨花三萜皂苷类化学成分研究

目的:研究木犀科茉莉属植物素馨花干燥花蕾的化学成分。方法:通过硅胶柱色谱、Sephadex LH-20柱色谱和重结晶等方法进行分离纯化,根据化合物的理化性质和波谱数据鉴定结构。结果:从素馨花干燥花蕾70%乙醇提取物中分离得到6个三萜皂苷类化合物,分别鉴定为3-O-α-L-吡喃鼠李糖基(1→2)-β-D-吡喃木糖基常春藤皂苷元-28-O-β-D-吡喃半乳糖基(1→6)-β-D-吡喃半乳糖酯苷(1)、常春藤皂苷元3-O-β-D-吡喃葡萄糖基(1→3)-α-L-吡喃阿拉伯糖苷(2)、2α,3β,23-trihydroxyolean-12-en-28-oic-O-β-D-glucopyranosyl ester(3)、常春藤皂昔元-3-O-β-D-吡喃木糖基(1→3)-α-L-吡喃鼠李糖基(1→2)-α-L-吡喃阿拉伯糖苷(4)、2α,3β,23-trihydroxyolean-12-en-28-oic-O-α-L-rhamnopyranosyl(1→4)-O-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl ester(5)、常春藤皂苷元-3-O-α-L-吡喃鼠李糖基(1→)2-α-L-吡喃阿拉伯糖苷(6)。结论:化合物1为新化合物,化合物26为首次从茉莉属植物中分离得到。

Triterpenoid saponins from flower bud of Jasminum officinale var. grandiflorum

OBJECTIVE: To study the chemical constituent bud of the flowers of Jasminum officinale var. grandiflorum. METHod: The compounds were isolated and purified by recrystallization and chromatography on silica gel and Sephadex LH - 20 column. Their structures were elucidated on the basis of physicochemical properties and spectral analysis. RESULT: Six triterpenoid saponins were identified as 3-O-alpha-L-rhamnopyranosyl (1 --> 2)-beta-D-xylopyranosyl- hederagenin-28-O-beta-D-galactopyranosyl (1 --> 6)-beta-D-galactopyranosyl ester (1), hederagenin-3-O-beta-D-glucopyranosyl (1 --> 3)-alpha-L-arabinopyranoside (2), 2alpha, 3beta, 23-trihydroxyolean-12-en-28-oic-O-beta-D-glucopyranosyl ester (3), hederagenin-3-O-beta-D-xylopyranosyl (1 --> 3)-alpha-L-rhamnopyranosyl (1 --> 2)-alpha-L-arabinopyranoside (4), 2alpha, 3beta, 23-trihydroxyolean-12-en-28-oic-O-alpha-L-rhamnopyranosyl (1 --> 4)-beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranosyl ester (5), hederagenin-3-O-alpha-L-rhamnopyranosyl (1 --> 2)-alpha-L-arabinopyranoside (6). CONCLUSION: Compound 1 is a new compound. Compounds 2, 3, 4, 5, 6 were isolated from the genus Jasminum for the first time.