| 高压氧治疗对脑梗死患者血清神经元特异性烯醇化酶的影响 |
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| 引用本文： | 何冬英,吴亦,李新平,吴健媛. 高压氧治疗对脑梗死患者血清神经元特异性烯醇化酶的影响[J]. 浙江医学, 2007, 29(6): 535-536,539 |
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| 作者姓名： | 何冬英 吴亦 李新平 吴健媛 |
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| 作者单位： | 322000,义乌市中心医院神经内科 |
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| 摘 要： | 目的 为观察脑梗死后血清神经元特异性烯醇化酶的动态变化，以及高压氧治疗后血清NSE的变化，判断高压氧治疗脑梗死的疗效。方法 将脑梗死患者84例，随机分为高压氧治疗组42例，常规治疗组42例，分别测定发病第1、2、3、12天的血清NSE水平，采用50例健康老年人的血清NSE作为正常对照组。结果 脑梗死患者血清NES水平明显高于正常组，P〈0．01，HBO治疗组第2、3、12天血清NSE水平与常规治疗组相比有显著差异，（第2天P〈0．05，第3天，第12天P均〈0．01）。结论 NSE可以作为反映脑梗塞患者脑细胞损伤程度的生化指标，早期高压氧治疗有助于减轻脑梗死病情。
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| 关 键 词： | 神经元特异性烯醇化酶 脑梗死 高压氧 |
| 修稿时间： | 2007-02-05 |
The effect of hyperbaric oxygen treatment on neuron-specific-enolase levels in patients with acute ischemic stroke |
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| HE Dongying, WU Yi, LI Xinping,et al.. The effect of hyperbaric oxygen treatment on neuron-specific-enolase levels in patients with acute ischemic stroke[J]. Zhejiang Medical Journal, 2007, 29(6): 535-536,539 |
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| Authors: | HE Dongying WU Yi LI Xinping et al. |
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| Affiliation: | Department of Neurology, Yiwu Centered Hospital, Zhejiang, Yiwu 322000, China |
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| Abstract: | Objective To investigate the effect of hyperbaric oxygen(HBO) treatment on neuron-specific-enolase(NSE) levels in patients with acute ischemic stroke.Methods Eighty four patients with acute ischemic stroke were divided into two groups randomly:HBO treatment group and general treatment group,42 cases in each.Serum levels of NSE were measured in all patients on d 1,2,3,12,and 50 healthy elderly subjects as controls.Results The serum level of NSE in acute ischemic stroke sufferers was higher than that of normal controls(P<0.01).The serum level of NSE in HBO group was markedly lower than that of general treatment group on d2,3,12(P<0.05).Conclusion NSE can be used as an indicator for brain cell damage,the HBO treatment can alleviate the brain damage induced by acute ischemic stroke effectively. |
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| Keywords: | Neuron-specific Enolase Cerebral infarction Hyperbaric oxygen |
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