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Calcimimetics maintain bone turnover in uremic rats despite the concomitant decrease in parathyroid hormone concentration
Authors:Juan M. Díaz-Tocados  María E. Rodríguez-Ortiz  Yolanda Almadén  Carmen Pineda  Julio M. Martínez-Moreno  Carmen Herencia  Noemi Vergara  M. Victoria Pendón-Ruiz de Mier  Rafael Santamaría  Cristian Rodelo-Haad  Antonio Casado-Díaz  Víctor Lorenzo  Catarina Carvalho  João M. Frazão  Arnold J. Felsenfeld  William G. Richards  Escolástico Aguilera-Tejero  Mariano Rodríguez  Juan R. Muñoz-Castañeda
Affiliation:1. Maimonides Institute for Biomedical Research (IMIBIC), Cordoba, Spain;2. Nephrology Service, Reina Sofia University Hospital, Cordoba, Spain;3. University of Cordoba, Cordoba, Spain;4. Spanish Renal Research Network (REDinREN), Institute of Health Carlos III, Madrid, Spain;5. Laboratory of Nephrology, Health Research Institute-Jiménez Diaz Foundation, Madrid, Spain;6. Internal Medicine Service, Reina Sofia University Hospital, Cordoba, Spain;7. Spanish Biomedical Research Networking Centre Consortium for the Area of Physiopathology of Obesity and Nutrition (CIBEROBN), Institute of Health Carlos III, Madrid, Spain;8. Department of Medicine and Animal Surgery, Cordoba, Spain;9. Clinical Management Unit for Endocrinology and Nutrition, Reina Sofia University Hospital, Cordoba, Spain;10. Network for Cooperative Research on Aging and Fragility (RETICEF) & Spanish Biomedical Research Networking Centre Consortium for the Area of Frailty and Healthy Aging (CIBERFES), Institute of Health Carlos III, Madrid, Spain;11. University Hospital of Tenerife, Nephrology Service, Canary Islands, Spain;12. Braga Hospital, Department of Nephrology, Braga, Portugal;13. Institute of Investigation and Innovation in Health (I3S), University of Porto, Porto, Portugal;14. National Institute of Biomedical Engineering (INEB), University of Porto, Porto, Portugal;15. Department of Nephrology, São João Hospital Center, Porto, Portugal;16. Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System and the David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA;17. Amgen Research, Thousand Oaks, California, USA
Abstract:
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  • Keywords:bone  calcimimetic  CaSR  chronic kidney disease  mineral metabolism  parathyroid hormone
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