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The Role of the Microbiome in Immunologic Development and its Implication For Pancreatic Cancer Immunotherapy
Authors:Vrishketan Sethi  Gerardo A Vitiello  Deepak Saxena  George Miller  Vikas Dudeja
Institution:1. Department of Surgery, Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida;2. S. Arthur Localio Laboratory, Department of Surgery, New York University School of Medicine, New York, New York;3. Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, New York
Abstract:
Keywords:Cancer Immunity  Immunotherapy  Microbiome  Bacteria  Pancreatic Cancer  CRC  colorectal cancer  CTX  cyclophosphamide  ETBF  GF  germ-free  IL  interleukin  ICI  immune checkpoint inhibitor  IFN  interferon  KPC  LP  lamina propria  PDAC  pancreatic ductal adenocarcinoma  PRR  pattern recognition receptor  SPF  specific pathogen–free  Th  T helper  TLR  Toll-like receptor  TME  tumor microenvironment  Treg  regulatory T cell
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