首页 | 本学科首页   官方微博 | 高级检索  
     


Bile-duct diameter at the porta hepatis and liver biopsies in Indian children with biliary atresia
Authors:V. Bhatnagar  M. K. Singh  D. K. Mitra
Affiliation:(1) Department of Paediatric Surgery, All India Institute of Medical Sciences, 110029 New Delhi, India;(2) Department of Pathology, All India Institute of Medical Sciences, 110029 New Delhi, India
Abstract:
Fibrous remnants from the porta hepatis and wedge biopsies of the liver were studied in 60 patients with biliary atresia. The patients were divided into three groups on the basis of bile duct diameter — I: no ducts; II: <50 mgrm; III: >50 mgrm. The liver damage was classified into three grades on the basis of ductular and parenchymal histopathologic changes and extent of inflammatory pathology. There was no correlation between severity of hepatic damage and duct diameter, although the levels of serum bilirubin and alkaline phosphatase varied in direct proportion to the degree of hepatic damage. There was an inverse relationship between age and duct diameter, but neither correlated with bile flow at surgery or in the postoperative period. The data suggest that Indian children with biliary atresia follow a different clinical course compared to those from Japan and Western countries.Correspondence to: V. Bhatnagar
Keywords:Biliary atresia  Jaundice  Bile ducts  Liver histology
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号