慢性前列腺炎气滞血瘀证证候计量诊断研究

目的探讨慢性前列腺炎气滞血瘀证计量诊断。建立计量诊断赋分表，确定诊断阈值，为慢性前列腺炎气滞血瘀证的宏观辨证提供数理统计学依据。方法选择门诊就诊的慢性前列腺炎患者，其中气滞血瘀证168例，非气滞血瘀证198例。参考气滞血瘀证中医诊断标准的四诊内容，结合临床病例确定量化标准的候选相关因素，应用统计比较方法选定相关因素；运用条件概率换算方法建立相关因素赋分表；应用最大似然法确定量化诊断阈值，根据临床流行病学试验研究方法进行量化诊断标准的回顾性和前瞻性检验。结果建立了慢性前列腺炎气滞血瘀证计量诊断赋分表，并确定量化诊断阈值为26。经回顾性和前瞻性检验，其敏感度、特异度、粗符合率、错判率、阳性似然比分别为：94．64％、88．89％、91.53％、8．47％、8．52；94．29％、90．32％、92．42％、7．58％、9．74。结论本计量诊断赋分表中各指标对慢性前列腺炎气滞血瘀证诊断有一定的客观性和代表性。该表经过回顾性、前瞻性检验考核，证明其具有较好的判别效果和一定的临床实用性。

Study on Quantitative Diagnosis of Stagnation of Qi and Blood Stasis Syndrome in Chronic Prostatitis

Objective To discuss the quantitative diagnosis of stagnation of Qi and blood stasis syndrome in chronic prostatitis. To make diagnosis chart and ensure diagnosis threshold level which provide statistics evidence for syndrome differentiation of TCM. Methods By the statistical ways, 168 cases of chronic prostatitis belong to stagnation of Qi blood and stasis syndrome and 198 cases of non-stagnation of Qi and blood stasis syndrome were investigated. To make a diagnosis chart and ensure diagnosis threshold level by applying the method of the maximum likelihood discriminatory analysis. Results The quantitative diagnosis chart was made and diagnosis threshold level was 26. According to the retrospective and prospective test, its sensitivity, especially degree, coincidence rate, error rate and positive likelihood ratio were 94.64%, 88.89%, 91.53%, 8.47%, 8.52 and 94.28%, 90.32%, 92.42%, 7.58%, 9.74. Conclusion The indexes of the quantitative diagnosis have good objectivity. According to the retrospective and prospective test, the diagnosis chart was proved to be practical.