| 文拉法辛快速撤药诱发低血压和急性心肌梗死 |
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| 引用本文： | 侯晓平,缪京莉. 文拉法辛快速撤药诱发低血压和急性心肌梗死[J]. 药物不良反应杂志, 2011, 13(1): 56-58 |
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| 作者姓名： | 侯晓平 缪京莉 |
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| 作者单位： | 人民解放军空军总医院老年心血管病科,北京,100142 |
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| 摘 要： | 1例91岁男性冠心病患者,近1年服用文拉法辛150 mg/d治疗抑郁/焦虑症。因精神症状加重拟停用文拉法辛换用他药,遂将文拉法辛减为75 mg/d,1 d后停用。次日晨患者意识突然丧失,10 min后恢复,血压50/30 mm Hg(1 mm Hg=0.133kPa)。给予多巴胺治疗。第2天患者心电图示急性心肌梗死;诊断为文拉法辛撤药综合征。给予阿司匹林、氯吡格雷、硝酸甘油及喹硫平等治疗,之后,患者明显好转,住院20 d出院。
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| 关 键 词： | 文拉法辛 撤药综合征 低血压 急性心肌梗死 |
Hypotension and acute myocardial infarction due to venlafaxine prompt withdrawal |
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| Hou Xiaoping,Miao Jingli. Hypotension and acute myocardial infarction due to venlafaxine prompt withdrawal[J]. Adverse Drug Reactions Journal, 2011, 13(1): 56-58 |
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| Authors: | Hou Xiaoping Miao Jingli |
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| Affiliation: | Hou Xiaoping,Miao Jingli(Department of Geratology and Cardiology,Air Force General Hospital of People's Liberation Army,Beijing 100142,China) |
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| Abstract: | A 91-year-old man with coronary artery disease received venlafaxine 150 mg/day for treatment of anxiety/depression for about one year.Because of his aggravated mental symptoms,the withdrawal of venlafaxine and the administration of other drugs were planned.Subsequently,venlafaxine was decreased to 75 mg/day,and then discontinued 1 day.The next day morning,the patient suddenly developed unconsciousness and,10 minutes later,he regained consciousness.His blood pressure was 50/30 mm Hg.He was treated with dopam... |
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| Keywords: | venlafaxine withdrawal symptom hypotension acute myocardial infarction |
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