首页 | 本学科首页   官方微博 | 高级检索  
     

右美托咪定对全麻患者气管插管时血流动力学变化的影响
引用本文:韩明杰,冯宇峰. 右美托咪定对全麻患者气管插管时血流动力学变化的影响[J]. 临床外科杂志, 2013, 0(11): 837-839
作者姓名:韩明杰  冯宇峰
作者单位:厦门大学附属第一医院麻醉科,361001
摘    要:目的 探讨右美托咪定对全麻患者气管插管时血流动力学变化的影响.方法 择期手术患者40例,随机分为M1、M2组,M1组麻醉诱导前给予右美托咪定0.5μg/kg,再以0.3 μg/(kg·h)速度持续输注.两组均给予咪达唑仑、芬太尼、丙泊酚、罗库溴铵麻醉诱导,气管插管.记录患者入室后、麻醉诱导前、插管前、插管即刻、插管1、3、5 min后的血压、心率.结果 M1组输注右美托咪定后,HR较基础值明显降低;麻醉诱导后各观察时刻,BP较基础值明显减低;M2组HR插管前低于基础值,插管后1 min大于基础值,BP在插管前与插管即刻明显小于基础值;M1组HR自诱导前各观察时刻、BP自插管时各观察时刻均低于M2组;M1组麻醉药诱导用量明显少于M2组.结论 麻醉诱导前给予右美托咪定0.5 μg/kg可较完善地抑制插管时的心血管反应,减少麻醉药用量.

关 键 词:右美托咪定  气管插管  血流动力学变化

Effect of dexmedetomidine on hemodynamic responses to tracheal intubation in patients with general anesthesia
HAN Ming-jie,FENG Yu-feng. Effect of dexmedetomidine on hemodynamic responses to tracheal intubation in patients with general anesthesia[J]. Journal of Clinical Surgery, 2013, 0(11): 837-839
Authors:HAN Ming-jie  FENG Yu-feng
Affiliation:. ( D-epartment of Anaesthsia ,the First Affiliated Hospital of Xiamen University , Xiamen 361001, China)
Abstract:Objective To investigate the effect of dexmedetomidine on hemodynamic responses to tracheal intubation in patients with general anesthesia. Methods Forty patients with selective operation were randomized into Group M1 and M2. Patients in the Group M1 received 0.5 μg/kg of dexmedetomi- dine before anesthesia induction and 0.3 μg/( kg · h)of dexmedetomidine continuous infusion subsequent- ly. Both groups received midazolam ,fentanyl, propofol and rocuronium for anesthesia induction. Blood pres- sure(BP) and heart rate(HR) were recorded after the patient~ arriving( baseline value),before the induc- tion,before the intubation, at intubation, and 1,3,5 minutes after intubation. Results After the dexme- detomidine infusion,the HR in the Group M1 decreased significantly compared with the baseline values. After the anesthesia induction, the BP also decreased. In the Group M2, the HR decreased before the intu- bation but raised at 1 st minute after intubation, and the BP decreased before and at the intubation. The HR from dexmedetomidine infusion and the BP from intubation in Group M1 decreased significantly than the values in M2 at all the deserved moments. The dosage for anesthesia induction in the Group M1 was less than that in the Group M2. Conclusion Before induction of anaesthesia,0.5 ug/kg of dexmedetomidine infusion can preferably inhibit the cardiovascular intubation response and reduce anaesthetic dosage.
Keywords:dexmedetomidine  tracheal intubation  hemodynamic responses
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号