子宫颈癌和子宫颈上皮内瘤变患者生命质量及相关因素分析

目的探讨宫颈癌和宫颈上皮内瘤变（CIN）患者的生命质量及其影响因素。方法采用宫颈癌患者生命质量测评量表（FACT-Cx）和自制问卷调查表对227例宫颈癌和CIN患者的生命质量及相关影响因素进行分析。结果宫颈癌和CIN患者FACT-G评分为（93.95±12.16）分,FACT-Cx评分为（143.78±16.19）分。生命质量评分在年龄、分期、是否放化疗比较,差异有统计学意义（P〈0.05）。logistic回归分析提示,诊断时分期越晚,采用放化疗患者的总体生命质量评分越低。年龄小、采用放化疗、诊断时分期晚的宫颈癌患者的其他忧虑（特异模块）评分低（P〈0.05）。结论临床分期和治疗方法是影响生命质量的重要因素,早期诊断宫颈癌、提高临床治疗效果对于宫颈癌患者的生命质量有帮助。

Research on the quality of life in patients with cervical cancer and its influential factors

Objective The aims of this study was to research the quality of life(QOL) in patients with cervical cancer or CIN and the influential factors.Methods Questionnaires of FACT-Cx and multiple items were administered to 227 patients with cervical cancer or CIN.Results The score of FACT-G was 93.95±12.16 and the score of FACT-Cx was 143.78±16.19.There were statistically differences in QOL of these patients at different ages,stages and treatments(P<0.05).Patients with advanced stages and those underwent combined therapy(chemotherapy and radiotherapy) had lower total scores of quality of life.Conclusions Stages and therapy methods were main influential factors of quality of life.Early diagnosis of cancer,improvement of the treatment effect might improve the quality of life of cervical cancer patients.