三七琥珀丸活血化瘀接骨续筋作用随机平行对照观察

目的]观察三七琥珀丸活血化瘀接骨续筋作用。方法]使用随机平行对照方法,将200例按掷硬币方法随机分为两组,治疗组110例三七琥珀丸(3次/d,1丸/次)。对照组90例伤科接骨片(3次/d,4片/次)。均从伤后或术后24h内给药,连续服药6周。观察疼痛、肿胀、肢体活动情况及拍摄骨折处X线并记录积分,血尿常规、肝功肾功、离子、心电图,毒副作用安全性评价。连续服药6周,随访2.5年判定疗效。结果]12例退出(实验组5例,对照组7例),9例未获随访(实验组5例,对照组1例)。实际179例完观察,均未报告出现不良反应。连续服药6周,随访6个月～2.5年,平均13个月。临床症状及分变化治疗组优于对照组(P<0.05),两组均有活血化瘀,消肿止痛,接骨续筋作用,用药前2周,两组无明显区别(P>0.05),4周后,治疗组消肿止痛接骨续筋作用明显好于对照组,临床疗效治疗组优于对照组(P<0.05)。结论]三七琥珀丸疗效确实,消肿止痛接骨作用明显,毒副作用小,值得广泛推广应用。

San Qi Hu Puo Pill Huoxue Huayu Jiegu Xujin Role of Randomized Controlled Observation

Objective]San Qi Hu Puo Pill Huoxue Huayu the Jiegu Xujin role.Method]The use of randomized controlled method,200 cases of 000 method were randomly divided into two groups,treatment group,110 cases of San Qi,Hu Puo Pill(3 times / d,1 pill/time).The control group of 90 cases Shangke Jiegu tablet(3 times / day,4/times).After injury or within 24h after administration,the medication for six weeks.Observation of pain,swelling,and physical activity in and shooting the X-ray of the fracture and record the points,urinalysis,liver function,renal function,ion,electrocardiogram,toxicity safety evaluation.Medication for six weeks,follow-up of 2.5 years to determine efficacy.Results]12 cases of exit(experimental group,five cases of the control group,7 cases),nine cases without follow-up(experimental group 5 cases,the control group(n=1)).Finished observe the actual 179 cases,no reports of adverse reactions.Medication for six weeks and followed for 6 months to 2.5 years,an average of 13 months.Clinical symptoms and the points change in the treatment group than the control group(P<0.05) in both groups Huoxue Huayu Xiaozhong Zhitong,the Jiegu Xujin role two weeks before treatment,and second,no significant difference(P>0.05) after 4 weeks Huoxue Huayu,treatment group of Jiegu Xujin by significantly better than the control group,the clinical efficacy of the treatment group than the control group(P<0.05).Conclusion]The San Qi,Hu,Puo Pill efficacy indeed,Xiaozhong Zhitong Jiegu obvious toxic side effects,be widely conducted.