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| 头孢替安治疗呼吸和泌尿生殖系感染50例及体外抗菌作用 | |
| 引用本文： | 吴菊芳,张婴元,汪复,周乐,张敬德,陆际晨,沈树新. 头孢替安治疗呼吸和泌尿生殖系感染50例及体外抗菌作用[J]. 中国新药与临床杂志, 1991, 0(5) |
| 作者姓名： | 吴菊芳 张婴元 汪复 周乐 张敬德 陆际晨 沈树新 |
| 作者单位： | 上海医科大学华山医院抗生素研究所，上海医科大学华山医院抗生素研究所，上海医科大学华山医院抗生素研究所，上海医科大学华山医院抗生素研究所，上海医科大学华山医院抗生素研究所，上海市儿童医院，上海金山县人民医院 上海 200040，上海 200040，上海 200040，上海 200040，上海 200040，200041，201500 |
| 摘 要： | 本文报道头孢替安的体外抗菌活性、临床疗效和安全性。结果表明头孢替安对部分金黄色葡萄球菌(金葡菌)和其他革兰阳性球菌和多数肠杆菌科细菌有良好抗菌作用。本品用于呼吸系、泌尿生殖系等感染50例(男22,女28,平均年龄31±25yr),成人2-6g/d,分2-3次静滴,儿童50-100mg/(kg·d),分2次静滴,疗程一般7-14d。治疗结果总有效率90％(其中痊愈率达62％)。不良反应较少见。 |
| 关 键 词： | 头孢替安/治疗应用 微生物敏感试验 呼吸道感染 尿路感染 |
Treatment of 50 patients with respiratory and urogenital infections with cefotiam and study of its antibacterial actions in vitro |
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| WU Ju-Fang,ZHANG Ying-Yuan,WANG Fu,ZHOU Le,ZHANG Jing-De,LU Ji-Chen,SHEN Shu-Xin. Treatment of 50 patients with respiratory and urogenital infections with cefotiam and study of its antibacterial actions in vitro[J]. Chinese Journal of New Drugs and Clinical Remedies, 1991, 0(5) | |
| Authors: | WU Ju-Fang ZHANG Ying-Yuan WANG Fu ZHOU Le ZHANG Jing-De LU Ji-Chen SHEN Shu-Xin |
| Affiliation: | WU Ju-Fang,ZHANG Ying-Yuan,WANG Fu,ZHOU Le,ZHANG Jing-De,LU Ji-Chen1,SHEN Shu-Xin2 |
| Abstract: | A study on microbiology, clinical efficacy and safety of cefotiam was undertaken. Cefotiam has good activity on Staphylococcus aureus, other gram-positive cocci and enterobacteriaceae. It was given to 50 patients (M 22, F 28; age 31±25yr) with respiratory tract and urogenital tract infections. The dosages were 2-6g/d for adults and 50-100mg/(kg.d) for children intravenously in 2-3 divided doses for 7-14d. Total response rate was 90% (cure rate being 62%). Adverse reactions were rare. |
| Keywords: | cefotiam/therapeutic use microbial sensitivity tests respiratory tract infections urinary tract infections |
| 本文献已被 CNKI 等数据库收录！ | |