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拉莫三嗪治疗双相情感障碍的研究进展
引用本文:倪开济,骆艳丽.拉莫三嗪治疗双相情感障碍的研究进展[J].上海医药,2014(19):20-23.
作者姓名:倪开济  骆艳丽
作者单位:同济大学附属同济医院心身医学科,上海200065
基金项目:基金项目:国家自然科学基金(项目批准号:81100821);上海市卫生局课题(2010-074)
摘    要:拉莫三嗪作为心境稳定剂治疗双相情感障碍已经应用于临床。在2013年最新的CANMAT指南中新增了拉莫三嗪单药或联合其他药物的治疗方案,提示目前应用拉莫三嗪治疗双相情感障碍已受到广泛关注。本文综述了近几年拉莫三嗪在治疗双相情感障碍各亚型中的临床研究、安全性及应用前景,为双相障碍的治疗提供新观点及新思路。

关 键 词:拉莫三嗪  双相情感障碍  治疗应用  安全性

Research progress of lamotrigine in the treatment of bipolar disorder
NI Kaiji,LUO Yanli.Research progress of lamotrigine in the treatment of bipolar disorder[J].Shanghai Medical & Pharmaceutical Journal,2014(19):20-23.
Authors:NI Kaiji  LUO Yanli
Institution:(Department of Psychosomatic Medicine, Tongji Hospital, Tongji University, Shanghai 200065, China)
Abstract:Lamotrigine as a mood stabilizer for the treatment of bipolar disorder has been used in clinical. The treatment programs of lamotrigine monotherapy or in combination with other drugs were added into the latest CANMAT guide in 2013, which indicated that the application of lamotrigine in the treatment of bipolar disorder is widely concerned. This review describes the clinical study, safety and the application prospect of lamotrigine in the treatment of some kinds of bipolar disorder subtypes so as to provide novel perspectives and new ideas for the treatment of bipolar disorder.
Keywords:lamotrigine  bipolar disorder  treatment application  security
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