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Increased mortality rates in young and middle-aged patients with malignant germ cell tumours

Authors:	Fosså S D Aass N Harvei S Tretli S

Affiliation:	The Norwegian Radium Hospital, Department of Clinical Research, Montebello, N-0310 Oslo, Norway. s.d.fossa@klinmed.uio.no

Abstract:	Cisplatin-based chemotherapy of malignant germ cell tumours (MGCT) has been reported to increase the risk of cardiovascular morbidity. A high incidence of second nongerm cell malignancies is well documented in MGCT survivors. The death risk due to these conditions is, however, more unknown in MGCT patients. Standard mortality rates (SMRs) were established in 3378 Norwegian MGCT patients treated from 1962 to 1997 aged

Keywords:	malignant germ cell tumours mortality nongerm cell cancer cardiovascular diseases
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