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| PGE1加甲钴胺治疗糖尿病周围神经病变 | |
| 引用本文： | 朱旭萍 周智广. PGE1加甲钴胺治疗糖尿病周围神经病变[J]. 湖南医科大学学报, 2001, 26(4): 343-344 |
| 作者姓名： | 朱旭萍 周智广 |
| 摘 要： | 目的：观察前列腺素E1（PGE1）与甲钴胺联合应用治疗糖尿病周围神经病变（DPN）疗效。方法：将72例DPN患者分为三组，分别予PGE1、甲钴胺治疗及其二者合用，共4周，对其治疗效果进行比较。结果：给予PGE1加甲钴胺治疗组DPN症状、神经传导速度改善明显好于单用PGE1或甲钴胺治疗组（P＜0．01）。结论：PGE1加甲钴胺联合用药对DPN症状改善优于单用药组。 |
| 关 键 词： | 糖尿病性周围神经病变 前列腺素E类 甲钴胺类 PGE1 DPN |
Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy] |
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| X P Zhu,Z G Zhou. Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy][J]. Bulletin of Hunan Medical University, 2001, 26(4): 343-344 | |
| Authors: | X P Zhu Z G Zhou |
| Affiliation: | Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University, Changsha 410011, China. |
| Abstract: | OBJECTIVE: To observe the clinical effect of combined treatment of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy(DPN). METHODS: Seventy two patients of DPN were divided into 3 groups, they were given the drug of prostaglandin E1 (PGE1), mecobalamin, PGE1 plus mecobalamin (combined therapeutic group) and compared the therapeutic effects respectively. RESULTS: The improvement of DPN symptoms and nerve conducting speeds of combined therapeutic group was obviously better than that of the single PGE1 group or mecobalamin group(P < 0.01). CONCLUSION: Combined therapy of PGE1 and mecobalamin is better than each of single drug for improvement of DPN symptoms. |
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