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Symbiotic collision tumour of the scalp: squamous cell carcinoma and malignant melanoma |
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| Authors: | Varitsara Mangkorntongsakul Er Tsing Vivian Tng James Scurry Ralph Gourlay |
| Affiliation: | 1. Gosford Hospital, Central Coast Local Health District, Gosford, NSW, Australia;2. Dermatology Registrar Royal Newcastle Centre, Hunter New England Health, John Hunter Hospital, Newcastle, NSW, Australia;3. Hunter Melanoma Unit, Newcastle, NSW, Australia;4. Pathology New South Wales, Hunter New England North, John Hunter Hospital, Newcastle, NSW, Australia |
| Abstract: | Cutaneous collision tumours are the co-existence of two tumours of different histopathological morphologies that coincide at the same or adjacent anatomical sites. A large scalp nodule excised from a 70 year-old man revealed a collision tumour composed of cells of squamous carcinoma (SCC) and malignant melanoma. Immunohistochemistry using dual staining for melanoma and squamous cell carcinoma demonstrated an unusual pattern; nests of melanoma cells surrounded by a layer of squamous carcinoma cells. The unique architecture observed in the case suggested a relationship between the two tumours. |
| Keywords: | collision tumour malignant melanoma melanoma squamous cell carcinoma symbiotic collision tumour |