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Cauda equina syndrome revealing neuroblastoma
Authors:Bourezgui M  Rafai M A  El Moutawakkil B  Boulaajaj F Z  Sibai M  Lezar S  Adil A  Benchkroun S  Kadiri R  Slassi I
Affiliation:1. Service de neurologie–explorations fonctionnelles, pavillon 30, CHU Ibn-Rochd, quartier des Hôpitaux, Casablanca, Maroc;2. Service de radiologie centrale, CHU Ibn-Rochd, Casablanca, Maroc;3. Service d’hématologie clinique–oncologie pédiatrique, CHU Ibn-Rochd, Casablanca, Maroc;1. Grand Rapids Orthopedic Residency Program, 1000 Monroe NW, Grand Rapids, MI 49506, USA;2. Orthopedic Associates of Michigan, Michigan State University, 1111 Leffingwell, Grand Rapids, MI 49525, USA;1. Institut Gustave-Roussy, département de médecine nucléaire et d''endocrinologie oncologique, faculté de médecine Paris-Sud, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France;2. Institut Gustave-Roussy, département de chirurgie, faculté de médecine Paris-Sud, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France;3. Institut Gustave-Roussy, département d''anatomopathologie, faculté de médecine Paris-Sud, 39, rue Camille-Desmoulins, 94805 Villejuif cedex, France;1. Department of Neurological Surgery, The Ohio State University, Wexner Medical Center, Columbus, Ohio, USA;2. Department of Head and Neck Surgery, The Ohio State University, Wexner Medical Center, Columbus, Ohio, USA;3. Department of Oncology Radiotherapy, The Ohio State University, Wexner Medical Center, Columbus, Ohio, USA
Abstract:IntroductionNeuroblastoma is the most common solid tumor of childhood. Neurological involvement is rare resulting from cord or nerve compression.Case reportA 7-year-old child was hospitalized for cauda equina syndrome. MRI showed retroperitoneal lesion with dumbbell intradural spreading. Blood and urinary catecholamine level were elevated confirming the diagnosis of neuroblastoma. She was treated with chemotherapy alone with partial neurological recovery.Discussion and conclusionCauda equina compression revealing neuroblastoma is exceptional especially at an early phase in the youngest patients. Treatment is based on surgical resection and/or chemotherapy and/or radiation therapy. Long-term prognosis is sometimes poor with neurological sequels.
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