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| GENE EXPRESSION OF TRANSFORMING GROWTH FACTOR β_1 TYPEII RECEPTOR IN HCC AND ITS CLINICAL SIGNIFICANCE | |
| 作者姓名： | 刘超 陈双 王捷 区庆嘉 |
| 作者单位： | LIU Chao(Department of General Summery，Memorial Hospital，Sun Yat-sen University of Medical Sciences，Guangzhou 510120，China）CHEN Shuang(Department of General Summery，Memorial Hospital，Sun Yat-sen University of Medical Sciences，Guangzhou 510120，China |
| 摘 要： | TransforminggrowthFactor-BetaI(TGF-0,)isanimportantnegativemediatoroflivercellproliferationandreplication.[1]ThreecellsurfaceproteinshavebeenidentifiedaccordingtotheirabilitytobindwithhighaffinitytoTGF-β1:typeI(55kd),type11(80kd),typeill(280kd)receptors.TypeII,possiblyinconjunctionwithtypeI,isthoughttobethereceptormediatingthesignaltransductionofgrowthinhibition.[2]BecausesometumorcelllinesandcertainhumancarcinomashavefewornoTGF-6,receptors,[3-6]weexploredandcomparedTGF-β1typeIIrecep… |
| 关 键 词： | Hepatocellular carcinoma Transforminggrowth factor-β1 receptor II Gene expression |
| 本文献已被 CNKI 等数据库收录！ | |