Surface Markers on Human B and T Lymphocytes |
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Authors: | M. JONDAL G. KLEIN M. B. A. OLDSTONE V. BOKISH E. YEFENOF |
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Affiliation: | Department of Tumor Biology, Karolinska Institute, Stockholm, Sweden, and Department of Immunopathology, Scripps Clinic and Research Foundation, La Jolla, California, USA |
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Abstract: | An association has been found between the Epstein-Barr virus (EBV) and complement (C3d) receptors on human lymphoid cells. The evidence was four-fold: there was a correlation between the expression of these two receptors; inhibition experiments showed that the binding sites probably are close to each other in the cell membrane, although not identical; EBV and complement receptors have been found to co-cap in either order; and lymphoid cell lines lacking complement receptors could not be superinfected with EBV. |
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