RhD血型阴性患者202例表型调查分析

目的：了解RhD阴性血型抗原分布及意义。方法对我院2013年1月—2014年12月57415例住院患者用血清学方法确认RhD阴性及表型。结果57415例住院患者血型中检出202例RhD血型阴性，占0.35%，RhD阴性住院患者的抗原表型分布主要为：ccdee（49.00%）、Ccdee（44.06%）、CCdee（3.96%）、ccdEe（1.49%）、CcdEe（0.99%）和ccdEE（0.50%）。结论 Rh血型抗原检测对降低输血风险、保障输血安全及进一步提高新生儿溶血病（HDN）的实验室诊断，维护母婴健康都有着非常重要的作用。

Investigation and analysis of phenotype in 202 patients with RHD negative blood group

ObjectiveTo understand the distribution and significance of C,C,E and e antigens in patients with RHD blood group negative blood type in our hospital.MethodsFrom January 2013 to December 2014 in our hospital,57 415 patients with RhD were confirmed by serological methods.ResultsDetected in 57415 cases of hospitalized patients blood type RhD blood group negative 202 cases(0.35%),The phenotypic distribution of RhD negative inpatients was mainly:ccdee(49.00%),Ccdee(44.06%),CCdee(3.96%),ccdEe(1.49%),CcdEe(0.99%)and ccdEE(0.50%). ConclusionRh blood group antigen detection to reduce the risk of blood transfusion to ensure the safety of blood transfusion and further improve the newborns hemolytic disease(HDN)maintenance of experimental diagnosis of maternal and child health has a very important role.