| 趋化因子基质细胞衍生因子1(SDF-1)及其受体CXCR4 |
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| 引用本文： | 杨文博. 趋化因子基质细胞衍生因子1(SDF-1)及其受体CXCR4[J]. 免疫学杂志, 2003, 0(Z1) |
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| 作者姓名： | 杨文博 |
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| 作者单位： | 第三军医大学新桥医院血液科 重庆 |
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| 摘 要： | 趋化因子及其受体在免疫和炎症反应、造血以及HIV感染等方面发挥重要作用,其中基质细胞衍生因子-1SDF-1及其受体CXCR4由于在造血干细胞迁移、归巢以及HIV感染中的作用而受到关注,并对其作用机制进行了探讨,现就SDF-1及其受体CXCR4的有关内容作一综述。
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| 关 键 词： | 趋化因子 SDF-1 CXCR4 |
Chemokine stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 |
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| YANG Wen-bo. Chemokine stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4[J]. Immunological Journal, 2003, 0(Z1) |
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| Authors: | YANG Wen-bo |
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| Abstract: | Chemokines and their receptors have important roles on immune, inflammation, hematopoiesis and HIV infection, etc . Close attention has been paid to chemokine stromal cell-derived factor-1 (SDF-1 ) and its receptor CXCR4 owing to their roles on migration and homing of hematopoietic stem cells and on HIV infection. The mechanisms have also been probed. This paper reviews the relevant contents with SDF-1/CXCR4. |
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| Keywords: | Chemokine SDF-1 CXCR4 |
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