上皮性卵巢癌预后因素分析

目的探讨影响上皮性卵巢癌预后的因素,为临床治疗提供依据。方法回顾分析1999年1月至2000年12月青岛大学医学院附属医院收治的100例卵巢癌患者的完整临床资料,用SPSS10.0软件进行Kaplan-Meier单因素和Cox多因素生存分析。计算各因素的风险系数并转化为评分,以评分计算生存概率。结果临床病理分期较早,细胞高分化,病理类型为子宫内膜样腺癌,无淋巴结转移,手术残余病灶≤2cm,术后规范化疗的患者预后较好。结论临床病理分期、病理分级、淋巴结转移情况、手术残余病灶大小、术后化疗情况、病理类型均是预测卵巢癌预后的独立因素。分析相关因素,并计算评分,可以预测卵巢癌患者的生存概率。

Prognosis factor in epithelial ovarian cancer

Objective:To explore the prognostic factors for epithelial ovarian tumors,in order to provide guidance for clinical therapy.Methods:The complete clinical data of 100 patients with epithelial ovarian carcinoma in from January 1999 to December 2000 were analyzed retrospectively and Kaplan-Meier survival analysis and Cox multiple factor survival analysis were conducted with SPSS10.0.The risk coefficient of each factor was calculated and transformed to score,then the survival probability was calculated with the score.Results:Patients with early clinical-pathology stage,high pathology grading,endometrioid adenocarcinom in pathology type,no lymphnode metastasis,less than 2cm residuals and adjuvent chemotherapy after operation had better prognosis.Conclusion:Clinical-pathology staging,patho-grading,the status of lymphnode metastasis,the size of the residuals,adjuvent chemotherapy and patho-type are independent prognostic factor of epithelial ovarian cancer.It is possible to estimate the prognosis of patients with ovarian cancer by analyzing these factors and calculated score.