老年女性急性ST段抬高心肌梗死患者临床及冠状动脉造影特点分析

目的探讨老年女性急性ST段抬高心肌梗死患者临床及冠状动脉造影特点。方法选择经急诊PCI诊治的年龄>60岁女性急性ST段抬高心肌梗死患者90例为老年女性组;另收集同期年龄匹配的男性急性ST段抬高心肌梗死患者190例为老年男性组,对比老年女性ST段抬高心肌梗死患者的临床及冠状动脉造影特点。结果老年女性组吸烟史及糖尿病患病率明显低于老年男性组,LDL-C、高敏C反应蛋白、白细胞介素6水平明显高于老年男性组,差异有统计学意义(P<0.05,P<0.01);老年女性组平均发病年龄明显高于老年男性组,3支病变比例明显低于老年男性组,差异有统计学意义(P<0.05,P<0.01)。结论女性心肌梗死发病年龄较晚,3支病变比例低;肥胖、LDL-C升高及炎性反应是女性心肌梗死的重要危险因素。

Analysis of clinical and coronary angiography of old women with acute ST-segment elevation myocardial infarction

Objective To study the clinical characteristics and coronary angiography of old women patients with acute ST-segment elevation myocardial infarction.Method 90 female patients with acute ST-segment elevation myocardial infarction(STEMI) treated by primary PCI treatment were selected(age>60 years).During the same period,190 male patients with acute STEMI were collected as a control(age > 60 years).The clinical and angiographic characteristics of female STEMI patients were analysed.Results The proportion of old female patients suffering from smoking and diabetes were significantly lower than that of male patients,while LDL-C and inflammatory response were significantly higher than that in the old male group;the mean age of female patients group was elder than that in male patients group(P<0.05,P<0.01).The three-vessel stenoses in old female patient group were lower than in old male patient group(P<0.05, P<0.01).Conclusion In the old STEMI patients,women's mean age was older than men.Obesity, LDL-C and inflammation were key factors for coronary heart disease to female.