老年急腹症患者全身炎症反应综合征和多器官功能不全综合 …

目的 分析全身性炎症反应综合征（ＳＩＲＳ）向多脏器功能不全综合征（ＭＯＤＳ）的发展过程，探索ＭＯＤＳ的防治策略。方法 回顾性分析２８０例老年急腹症患者的ＳＩＲＳ和ＭＯＤＳ的临床资料。结果 老年急腹症患者入院时，ＳＩＲＳ的发生率４１．４％，其中ＭＯＤＳ发生率１２．９％，病死率１０．３％；经治疗（包括手术和保守治疗）４８小时后，仍伴有ＳＩＲＳ的患者３９例中，１５例发展为ＭＯＤＳ。２８０例老年急腹症患者

A clinical study on systemic inflammatory response syndrome and multiple organ dysfunction syndrome in elderly patients with acute abdomen

Objective To analyse the development from systemic inflammatory response syndrome (SIRS) to multiple organ dysfunction syndrome (MODS) and probe the therapeutic strategies for MODS in elderly patients. Methods The clinical data of SIRS and MODS in 280 elderly patients with acute abdomen were retrospectively studied. Results On admission, the morbidity rate of SIRS was 41 4% and MODS 12 9% successively.The mortality rate of the elderly patients with SIRS was 10 3%. After 48 hours of therapy, MODS developed in 15(38 5%) of the 39 cases remaining to have SIRS. Of all the 280 elderly patients, 17 cases (6 1%) developed MODS and 14 (82 3%) patients died. Conclusions The outcome of the patients with acute abdomen may be improved if SIRS is diagnosed earlier, especially the cause of SIRS still remaining after 48 hours therapy. Active control of the inflammatory response is the key to improve the prognosis of acute abdomen in elderly.