The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis |
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| Authors: | Zhang Xu Dong Gillespie Susan K Borrow Jodie M Hersey Peter |
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| Affiliation: | Immunology and Oncology Unit, Room 443, David Maddison Clinical Sciences Building, Cnr. King & Watt Streets, Newcastle, NSW 2300, Australia. |
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| Abstract: | |
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| Keywords: | TRAIL, TNF-related apoptosis-inducing ligand SBHA, suberic bishydroxamate HDAC, histone deacetylases IAP, inhibitor of apoptosis proteins c-IAP, cellular inhibitor of apoptosis XIAP, X-linked IAP ICAD, inhibitor of caspase-activated DNase PARP, poly(ADP-ribose) polymerase FLIP, FLICE/caspase-8 inhibitory protein MAb, monoclonal antibody Ab, antibody FLICE, FADD-like interleukin-1 converting enzyme |
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