重症药疹38例临床分析

目的 提高对重症药疹的临床认识,提高治愈率.方法 分析我科1996～2006年间住院重症药疹患者38例,其中大疱性表皮坏死松解型(BENL)21例,重症多形红斑型(EMM)14例,剥脱性皮炎型(ED)3例,治疗以中大剂量皮质类固醇激素为主.结果 治愈37例,死亡1例.结论 解热镇痛药在致敏药物中占首位,早期应用足量皮质类固醇激素是提高治愈率的关键.

Clinical analysis of 38 cases of inpatient with severe drug eruption

Objective To further realizing the clinical features of severe drug eruption and improve the cure rate. Methods Thirty eight cases of in - patient with severe drug eruption in the Department of Dermatology from 1996 to 2006 were analyzed. Among them there were 21 eases of bullous epidermal necrulysis, 14 eases of erythema muhiforme major, 3 case of exfoliative dermatitis. They were treated with different eortieostereid dosage. Results Thirty seven cases were cured and 1 case died. Condusion analgesics and antipyreties drugs are the most common causes of severe drug eruption among this group patients. Early and sufficient cortieosteruid treatment of the patients with severe drug eruption is the key for cure.