Non-pharmacological management of a hemodynamically significant patent ductus arteriosus |
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| Affiliation: | 1. Department of Paediatric and Newborn Medicine, Coombe Women and Infants University Hospital, Dublin, Ireland;2. Neonatal Intensive Care Unit, Institute for the Care of Mother and Child, Prague, Czech Republic;3. INFANT Centre, Cork University Maternity Hospital, University College Cork, Ireland;4. Department of Paediatrics and Child Health, University College Cork, Ireland;5. Department of Paediatric Cardiology, Our Lady''s Children''s Hospital Crumlin, Dublin, Ireland;6. UCD School of Medicine, Dublin, Ireland;7. 3rd Faculty of Medicine, Charles University, Prague, Czech Republic;1. Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy;2. Department of Neurosciences, Psychology, Drug Research and Child Health, Careggi University Hospital of Florence, Italy;3. NICU Fondazione IRCCS Ca'' Granda Ospedale Maggiore Policlinico, Milan, Italy;4. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy;5. Neonatal Intensive Care Unit, Department of Public Health and Pediatrics, University of Turin, Turin, Italy;6. NICU, Ca'' Foncello Hospital, Treviso, Italy;7. Division of Neonatology, “V. Buzzi” Children''s Hospital – ASST FBF/Sacco, Milan, Italy;8. Neonatal Intensive Care Unit, University Aldo Moro of Bari, Bari, Italy;9. Neonatal Intensive Care Unit, Department of Women''s and Children''s Health, “Di Venere” Hospital of Bari, Bari, Italy;10. Neonatal Intensive Care Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy;11. Department of Maternal and Child Health, Division of Neonatology and Neonatal Intensive Care, Casilino General Hospital, ASL RM B, Roma, Italy;12. Department of Woman''s and Child''s Health, Azienda Ospedaliera di Padova, University of Padua, Padua, Italy;13. Division of Neonatology, Section of Pediatrics, Department of Translational Medical Sciences, Università Federico II of Naples, Naples, Italy;14. Neonatal Intensive Care Unit, Institute of Puericulture and Neonatal Section, Department of Surgery, University of Cagliari, Cagliari, Italy;15. Neonatal Intensive Care Unit, University Hospital of Foggia, Foggia, Italy;p. Clinical Trials Coordinating Center, Careggi University Hospital of Florence, Florence, Italy;1. Division of Neonatology, Wright State University Boonshoft School of Medicine, Pediatrix Medical Group, Dayton, OH;2. Division of Neonatology, Department of Pediatrics, Baylor College of Medicine, The Children''s Hospital of San Antonio and Pediatrix Medical Group, San Antonio, TX;3. The Pediatrix Center for Research, Education, and Quality, MEDNAX, Inc, Sunrise, FL;4. Division of Neonatology, Greenville Health System, University of South Carolina School of Medicine – Greenville, Greenville, SC;5. Division of Neonatology, Department of Pediatrics, Baylor University Medical Center and Pediatrix Medical Group, Dallas, TX |
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| Abstract: | ![]()
The association between the patent ductus arteriosus (PDA) and neonatal morbidity, mortality and poor neurodevelopmental outcome in later childhood has been the focus of intense debate for decades. The lack of evidence supporting therapeutic strategies aimed at achieving PDA closure has led to the widespread adoption of conservative management aimed at mitigating the impact of shunt volume without achieving ductal closure. In this article, we review this management approach, describe the supportive evidence and potential complications associated with this strategy. |
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| Keywords: | Patent ductus arteriosus Management |
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